Medical-Grade Skincare for Anti-Aging

Our anti-aging skincare collection is built on protection from environmental aggressors, correction of visible fine lines, and restoration of the skin's natural moisture barrier. At Dermshop, our board-certified dermatologists bring their expertise to the forefront with a selection of the best topical anti-aging solutions backed by science and data.

Discover an assortment of retinols, anti aging serums, the best skincare for mature skin, wrinkle repair creams and more. These formulations go beyond traditional cosmetics, offering therapeutic benefits that genuinely address the signs of aging.

Vivier C E Peptides serum bottle with dropper on a stone surface and stone wall background

Prevent

Neutralize free radicals and environmental stressors
Woman with a towel wrapped around her head doing her skincare routine

Correct

Stimulate cell turnover and production
Skinceuticals Triple Lipid Restore 2-4-2 jar on a textured beige background

Replenish

Restore essential moisture, hydration and lipids
colorescience sunforgettable face shield classic

Protect

Prevent photoaging

To avoid dryness, peeling and irritated skin, we recommended starting slowly with retinol. Start with retinol once a week and gradually increase frequency as your skin builds tolerance. Always pair your night time retinol with a nourishing moisturizer or hydrator to support the skin barrier.

In terms of anti-aging skincare, prevention is more effective than correction. If you're in your early 20s, we recommend incorporating antioxidants like vitamin C protect against UV damage. When you get into your late 20s or early 30s, you can start a retinol serum to maintain collagen production and cellular turnover before deep lines begin to form.
Eye Creams Moisturizers Retinol Serums Peptides Growth Factor
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Glymed Radiant Serum bottle on a white background

Glymed Plus Radiant Serum with 1% Mandelic Acid

$122.00 $103.70 CAD
    A white cylindrical cosmetic bottle labeled 'iS CLINICAL YOUTH COMPLEX' with blue text and logo, centered on a plain white background. A close-up of hands dispensing a white cream from a silver cylindrical cosmetic pump bottle labeled 'iS Clinical YOUTH COMPLEX'

    IS Clinical Youth Complex

    $268.80 CAD
      A silver cylindrical bottle of IS Clinical Youth Eye Complex skincare serum, featuring a metallic silver cap and a white label with blue text, centered on a plain white background. A close-up of a person's hands holding a silver cosmetic pump bottle of iS Clinical Youth Eye Complex and dispensing a small white cream against a plain light gray background.

      IS Clinical Youth Eye Complex

      $198.00 CAD
        IS Clinical Active Serum in a cobalt blue glass dropper bottle with a silver collar and white dropper top, centered on a plain white background. A close-up of a person's hands holding an open cobalt blue dropper bottle and lifting the dropper, with clear serum droplets falling. The bottle says iS Clinical Active Serum

        IS Clinical Active Serum

        $244.80 $208.00 CAD
          A frosted glass skincare dropper bottle with a metallic silver collar and a white dropper cap, labeled 'iS CLINICAL BRIGHTENING SERUM' on a plain white background. A close-up of a hand holding a small frosted glass dropper bottle of iS Clinical Brightening Serum while another hand dispenses a clear liquid from a silver dropper above it, against a plain light gray background.

          IS Clinical Brightening Serum

          $240.00 $204.00 CAD
            IS Clinical C-Eye Serum Advanced in an amber glass dropper bottle with a silver collar and white dropper cap, on a white background. A close-up of a hand holding an amber glass dropper bottle iS Clinical C Eye Serum while another hand drops clear serum from a silver dropper above it, against a plain light gray background.

            IS Clinical C Eye Serum

            $117.60 $100.00 CAD
              An amber glass dropper bottle of IS Clinical Super Serum Advance+ on a clean white background. A close-up of a hand holding a glass dropper of iS Clinical Super Serum above another hand, with a single drop of golden-yellow liquid about to fall. The background is a clean, neutral light gray.

              IS Clinical Super Serum Advance

              $272.40 $231.54 CAD
                A bottle of IS Clinical Pro-Health Serum in an amber glass dropper bottle with a silver collar and white dropper cap, centered on a plain white background. A close-up of a hand holding an amber glass dropper bottle while another hand drops a golden serum above it, against a plain light gray background. The bottle label reads iS Clinical PRO-HEAL SERUM ADVANCE+

                IS Clinical Pro-Heal Serum

                $272.40 $231.54 CAD
                  IS Clinical Reparative Moisture Emulsion in a tall, cylindrical silver bottle with a reflective cap, set against a plain white background. A close-up of a person's hands holding and dispensing a silver and blue cosmetic emulsion bottle of iS Clinical Reparative Moisture Emulsion against a solid gray background.

                  IS Clinical Reparative Moisture Emulsion

                  $181.20 CAD
                    A silver squeeze tube of iS Clinical Sheald Recovery Balm with blue text and logo, centered on a white background with a soft reflection below. A smooth, glossy swipe of white cream iS Clinical Sheald Recovery Balm on a solid light gray background.

                    IS Clinical Sheald Recover Balm

                    $136.80 CAD